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Saturday, 04 July 2009

  • Is it safe for men with heart disease to use sildenafil (Viagra)?

    Sildenafil has been found to be effective and safe in the treatment of erectile dysfunction in men with stable heart disease due to atherosclerosis of the coronary arteries, provided that they are not on nitrates. The real concern is not as much the safety of sildenafil but the risk of sexual activity in triggering heart attacks or abnormal heart rhythms in patients with heart disease.

    The risk of developing heart attacks or abnormal heart rhythms during sex is low in men with well controlled hypertension, mild disease of the heart's valves, well controlled heart failure, mild and stable angina (with a favorable treadmill stress test), successful coronary stenting or bypass surgery, and a remote history of heart attack (more than 8 weeks previously). Sildenafil can be used safely in men in these low risk groups.

    The risk of heart attack or abnormal heart rhythms during sex is higher in men with unstable angina (angina that occurs at rest or with minimal exertion), poorly controlled hypertension, moderate to severe heart failure, moderate to severe disease of the heart's valves, recent heart attack (less than 2 weeks previously), potentially life threatening disorders of heart rhythm such as recurrent ventricular tachycardia, and moderate to severe disease of the heart's muscle. In these men, doctors usually stabilize or treat the heart conditions before prescribing sildenafil.


    Before starting sildenafil for erectile dysfunction, a doctor may need to determine whether the heart can safely achieve the workload necessary for sexual activity. For example, in men with coronary artery heart disease, a doctor may perform a treadmill stress test to determine whether there is adequate blood supply to the heart muscle while exercising at levels comparable to sexual activity.


Friday, 19 October 2007

  • Doctors warn against anti-impotence “Remedies” in Hong Kong

    Doctors have warned against “herbal remedies" for Impotence treatment sold over-the-counter in Hong Kong after most of them were found to include untested variants of well-known anti-impotence drugs.

    These variants are copies of controlled drugs but they are slightly modified in their chemical formation to get away with patent and other drug-related laws.

    Cranked out unlawfully, these chemicals are not tested for their effectiveness or safety and can have impulsive, adverse effects. They are added implicit into "health products," which do not come under stringent tests in most countries.Writing in the latest issue of the Hong Kong Medical Journal, the scientists said they studied 26 anti-impotence products sold in convenience stores and pharmacies.

    Although their packaging declared that they limited only "herbal ingredients," variants of sildenafil and vardenafil were found in 14 of them. Sildenafil was found in one product.Sildenafil and vardenafil are generic names for their better known trade labels Viagra and Levitra, respectively, and they are prescribed drugs in Hong Kong.

    "Without going through the rigorous drug testing procedure, the bad effects of these chemicals remain largely unidentified and irregular," they warned, as they called for urgent and more effective observation and control.” The medical profession and the public should be alerted to this under-recognized threat."

    "Unlike the parent pharmaceutical, no formal studies have been performed to assure the safety and efficacy of these analogues," the researchers wrote.” Evidently, the adverse effects of drug analogues are highly irregular and the utilization of such products is dangerous."

    Analogues have also been found in so called "natural" or "herbal" slimming products in Hong Kong and at least one woman has died of a cardiac arrest after consuming them.

    Source: Reuters    

Friday, 12 October 2007

  • Cialis boost Sexual function of prostate cancer survivors

    According to research done by Dutch scientists The widely used prescription drug Cialis for treatment of erectile dysfunction in men increases the sexual function of prostate cancer survivors.

    Prostate cancer is the most commonly diagnosed cancer in men. But after treatment, some patients report difficulty in achieving an erection sufficient for sexual activity -- a medical condition called erectile dysfunction or ED. In the Dutch study, physicians wanted to test whether the drug Tadalafil, which sells under the brand name Cialis, would help prostate cancer survivors with ED, for those who were treated with three-dimensional conformal radiation therapy.

    In what is believed the first randomized examination of its type, successful intercourse was reported in 48 percent of the survivors who took Tadalafil versus 9 percent of the men who were given placebo. There was also a reported advancement of the quality of erections in 67 percent of the patients, versus 20 percent of the placebo group.

    The research conducted at the Erasmus MC-Daniel den Hoed Cancer Center in Rotterdam is detailed in the International Journal of Radiation Oncology Biology Physics.

    Source: United Press International

       

Friday, 05 October 2007

  • Fake Viagra that netted pill gang millions

    A man described as the UK linchpin of a global conspiracy to sell fake medicines over the internet was yesterday sentenced to four and a half years in prison following what police described as the biggest counterfeit drugs bust in British history.

    Ashish Halai, 33, masterminded the multimillion-pound movement of fake Viagra and other lucrative drugs from factories in China, India and Pakistan into the UK and then on to the Bahamas and the US.Three other men were also convicted of conspiracy charges; Gary Haywood, 58, Halai's brother-in-law Ashwin Patel, 24, and Pakistan-based Zahid Mirza, 45, are yet to be sentenced. Four others face a retrial after the jury failed to agree verdicts.

    Sentencing Halai at the end of a nine-month trial at Kingston crown court, Judge Nicholas Price told him: "I'm satisfied that greed is the overriding motivation for such offences. I have absolutely no doubt that large profits were made...You are undoubtedly a highly intelligent man. I accept that you have business acumen which should have been better employed in legitimate enterprise." It was a chance find that led to the unravelling of a massive global prescription drug fraud in which UK criminals were key players. Customs staff at Stansted airport opened a package containing plastic tubs of fish protein and dog protein. Inside were 12,000 little blue diamond-shaped pills.

    It was counterfeit Viagra, destined for thousands of young men seeking pleasure and older men seeking help for impotence not only in the UK but in other countries around the world. The tablets, repackaged to look like the original, would be sent out to customers who had ordered Viagra through internet websites, either because they were too embarrassed to see a GP or because they did not qualify for a prescription. What few realise is that most lifestyle drugs sold on the internet are fake.

    Source : The Guardian

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